Vitamin D Status and Sepsis Outcomes: A PRISMA-Compliant Umbrella Review and Meta-Analysis - PubMed
7 hours ago
- #sepsis
- #meta-analysis
- #vitamin D
- Vitamin D deficiency is linked to increased sepsis risk, higher mortality, and greater disease severity.
- Stronger associations between vitamin D deficiency and adverse sepsis outcomes are observed in children and neonates.
- VDR gene polymorphisms modestly increase sepsis susceptibility.
- Vitamin D supplementation does not consistently reduce sepsis risk or mortality.
- Vitamin D deficiency serves as a robust marker for sepsis risk and poor prognosis.