Progression of diabetic retinopathy during pregnancy in a woman with ABCC8-MODY - PubMed
7 days ago
- #pregnancy
- #diabetes
- #retinopathy
- A 31-year-old woman with ABCC8-MODY experienced rapid progression of diabetic retinopathy during pregnancy.
- She was diagnosed with diabetes at age 11 and managed with oral agents before switching to insulin therapy during pregnancy.
- At 22 weeks gestation, her retinopathy progressed to bilateral active proliferative diabetic retinopathy, requiring multiple panretinal photocoagulation (PRP) sessions.
- She delivered a healthy baby at 38 weeks via elective caesarean section without complications.
- Postnatally, her retinopathy persisted, requiring additional PRP, and she was later switched back to oral agents after breastfeeding.
- This is the first reported case of rapid retinopathy progression during pregnancy in ABCC8-MODY, highlighting risks of end-organ disease in rare diabetes forms.