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Decoding a Disorder at the Interface of Mind and Brain

21 hours ago
  • #medical-research
  • #neurology
  • #mental-health
  • Tracey McNiven developed a persistent cough followed by numbness and loss of control in her legs, leading to hospitalization.
  • Functional Neurological Disorder (FND) affects a third of neurology clinic patients with unexplained symptoms like paralysis, seizures, or blindness.
  • Historically, FND was called hysteria or conversion disorder, reflecting outdated beliefs about psychological causes.
  • Modern research uses fMRI to study brain changes in FND, revealing altered connectivity in motor and emotional processing regions.
  • Predictive processing theory suggests FND arises from abnormal brain predictions about body function, influenced by stress or trauma.
  • Treatments include specialized physiotherapy, cognitive-behavioral therapy (CBT), and transcranial magnetic stimulation (TMS), but recovery remains challenging.
  • FND clinics and advocacy groups like FND Hope are raising awareness, though stigma and diagnostic debates persist.