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Investigating the Mechanism of Rehmannia glutinosa-Ephedra sinica in heart failure with preserved ejection fraction by Network Pharmacology, Metabolomics and Experimental Validation - PubMed

2 months ago
  • #Ferroptosis
  • #Cardiovascular Research
  • #Herbal Medicine
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  • MD可改善HFpEF模型中的代谢紊乱、心脏重构和舒张功能障碍
  • 作用机制涉及PI3K/AKT信号通路及通过GPX4/ACSL4途径调控铁死亡
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  • 研究结果提示MD的心脏保护作用与代谢调节和铁死亡调控相关