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DNA seen through the eyes of a coder (or, If you are a hammer, everything looks like a nail) - Bert Hubert's writings

a day ago
  • DNA is like byte-compiled code for a virtual machine called the nucleus, using a digital but non-binary language with four bases (T, C, G, A) and three-letter codons that encode amino acids.
  • Transposable elements (jumping DNA) are analogous to position-independent code, allowing stretches of DNA to move around the genome.
  • Conditional compilation (#ifdef) is seen in how cells express only relevant genes, with stem cells being like un-#ifdefed code that can differentiate into any cell type.
  • Epigenetics and imprinting act like runtime binary patching, modifying gene activation without altering DNA sequence, and can be heritable.
  • Junk DNA (introns) functions like comments that are physically spliced out, and may aid in DNA folding, though its exact role remains debated.
  • Cell division (fork()) can lead to tumors (fork bombs) when safeguards fail, similar to the halting problem in computing.
  • The genetic code uses degenerate encoding (Reed-Solomon-like) to protect against errors, and highly conserved genes (like histones) are 'holy code' that rarely mutate.