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Alzheimer's proteing detected in long Covid patients

21 days ago
  • Post-COVID neurocognitive patients showed a 59% increase in plasma pTau-181, a biomarker linked to Alzheimer's and neurodegeneration.
  • Tau elevations were most pronounced in individuals with neurocognitive symptoms lasting over 1.5 years, suggesting prolonged Long COVID may worsen neurological injury.
  • Researchers emphasize the need for further studies, including neuroimaging and broader population samples, to confirm whether elevated blood tau indicates progressive brain pathology.
  • The study analyzed 227 WTC responders with neurological post-acute sequelae of COVID-19, compared to controls, who showed no tau increase.
  • Findings imply COVID-19 virus may contribute to abnormal tau production over time, raising concerns about long-term neurodegenerative risk.