Dekonstruktion des Programmcodes des BioNTech/Pfizer SARS-CoV-2 Impfstoffes - Bert Hubert's writings
a day ago
- The BioNTech/Pfizer SARS-CoV-2 mRNA vaccine (BNT162b2) consists of a digital code of 4284 characters, produced by a DNA printer and delivered as RNA in a lipid package.
- RNA is a fragile, RAM-like version of DNA; the vaccine's need for ultra-cold storage is due to RNA's instability.
- The vaccine code uses modified 'U' bases (1-Methyl-3'-Pseudouridylyl) to evade the immune system, a trick akin to cybersecurity bypassing firewalls.
- The 5' untranslated region (UTR) optimizes ribosome docking and protein translation, based on α-globin genome for high efficiency.
- A signal peptide directs the Spike protein to leave the cell via the endoplasmic reticulum, with codon optimization (more C and G bases) to enhance production.
- The Spike protein coding region features two proline substitutions that lock the protein in its active form, increasing vaccine efficacy against the actual virus.
- The 3' UTR and poly(A) tail of the mRNA enhance stability and translation efficiency, with a proprietary linker sequence for optimization.
- All modifications (codon optimization, U replacement, proline changes) are designed to increase RNA stability, evade immune detection, and produce a stable, immunogenic Spike protein.