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Long Covid symptoms linked to measurable damage in the brain's dopamine system

3 hours ago
  • Long COVID patients show an 18% reduction in dopamine-releasing nerve terminals in the brain, as measured by PET imaging.
  • This dopamine loss correlates with specific symptoms: apathy, memory problems, and slowed physical movements.
  • The study suggests that dopamine-boosting treatments could be a new therapeutic direction for long COVID.
  • Structural MRI scans often appear normal, but molecular imaging reveals underlying brain chemistry changes.
  • The findings are from a small case-control study (24 patients) and need confirmation in larger, diverse groups.
  • The biological mechanism may involve inflammation damaging dopamine neurons, but causality is not proven.