A Science Experiment: part 2 - Bert Hubert's writings
a day ago
- Created and released SkewDB, the largest comprehensive database of GC/TA skews in 25,000 bacterial chromosomes.
- Open-sourced the software that processes 120GB of public NCBI data to generate the database.
- Provided a Jupyter notebook for easy exploration and plotting of the dataset.
- Discovered a method to predict GC/TA skew in Firmicute bacteria, potentially resolving existing debates.
- Identified dozens of bacteria with unexplained asymmetries, including strands with no GC skew and uneven strand sizes.
- Acknowledged the importance of open data sharing and plans to publish a preprint for peer review.