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COVID-19 Predictions & Rampant Speculation: May 2020 - Bert Hubert's writings

a day ago
  • Monoclonal antibodies (mabs) are predicted to be the first game-changing COVID-19 medicines, useful for both prevention and treatment.
  • Rapid antigen tests, even if not highly sensitive, are valuable for identifying infectious people from a public health perspective.
  • COVID-19 will drive breakthroughs in vaccine technologies like mRNA, potentially benefiting flu shots and cancer medicine.
  • Epidemiological models often fail due to ignoring variability in susceptibility and exposure; their overreliance is criticized.
  • Vitamin D and sunlight exposure likely play a significant role in immune system performance against COVID-19.
  • COVID-19 spread shows overdispersion, where most individuals infect no one, while a few cause superspreading events.
  • The pandemic may advance molecular biology and medicine, similar to HIV's impact, and push scientific journals towards open access.
  • Second waves in regions with prior outbreaks may be milder due to partial immunity from sub-infective exposures.
  • Contact tracing apps may be less useful than quickly identifying superspreading events.