Psychiatric adverse events following Covid-19 vaccination

7 hours ago

Study investigated psychiatric adverse events (AEs) after COVID-19 vaccination using a population-based cohort in Seoul, South Korea.
Data from KNHIS claims database; 2,027,353 participants divided into vaccinated (1,718,999) and non-vaccinated (308,354) groups.
Cumulative incidence at 3 months was higher for depression, anxiety/dissociative/stress-related/somatoform disorders, sleep disorders, and sexual disorders in vaccinated group.
Schizophrenia and bipolar disorder had lower cumulative incidence in vaccinated group.
COVID-19 vaccination significantly increased risks of depression (HR=1.683), anxiety-related disorders (HR=1.439), and sleep disorders (HR=1.934), but reduced risks of schizophrenia (HR=0.231) and bipolar disorder (HR=0.672).
Special caution is needed for additional vaccination in populations vulnerable to psychiatric AEs.

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